Table 1 Baseline Characteristics
From: Mendelian randomization: estimation of inpatient hospital costs attributable to obesity
| Underweight [BMI < 18.5] | Normal [25 > BMI ≥ 18.5] | Overweight [30 > BMI ≥ 25] | Obese Class 1/2 [40 > BMI ≥ 30] | Obese Class 3 [BMI ≥ 40] | Total | ||
|---|---|---|---|---|---|---|---|
| N (%) | N (%) | N (%) | N (%) | N (%) | N (%) | ||
| Weighted GRS | Mean (SD) | 3.07 (0.53) | 3.11 (0.52) | 3.16 (0.52) | 3.21 (0.52) | 3.29 (0.52) | 3.16 (0.52) |
| Median (Q1, Q3) | 3.06 (2.70, 3.42) | 3.10 (2.75, 3.46) | 3.15 (2.80, 3.51) | 3.21 (2.86, 3.56) | 3.29 (2.94, 3.65) | 3.15 (2.80, 2.51) | |
| BMI t0 | Mean (SD) | 17.6 (0.8) | 22.9 (1.5) | 27.3 (1.4) | 33.1 (2.5) | 43.6 (3.5) | 27.4 (4.7) |
| Median (Q1, Q3) | 17.9 (17.3, 18.2) | 23.1 (21.8, 24.1) | 27.2 (26.1, 28.5) | 32.5 (31.1, 34.6) | 42.5 (41.1, 45.1) | 26.7 (24.1, 29.9) | |
| Sex | Male | 514 (21%) | 55,141 (35%) | 109,199 (53%) | 53,078 (49%) | 2818 (32%) | 220,750 (45.8%) |
| Female | 1980 (79%) | 102,189 (65%) | 96,208 (47%) | 55,004 (51%) | 5996 (68%) | 261,377 (54.2%) | |
| Age | Mean (SD) | 55.4 (8.1) | 55.7 (8.2) | 57.0 (8.1) | 60.0 (7.9) | 55.6 (7.7) | 56.5 (8.1) |
| Median (Q1, Q3) | 56 (49, 62) | 57 (49, 63) | 59 (51, 64) | 58 (51, 63) | 56 (50, 62) | 58 (50, 63) | |
| Ethnicity | White | 2319 (93%) | 149,143 (95%) | 193,899 (94%) | 101,231 (94%) | 8157 (93%) | 454,127 (94%) |
| Black | 10 (< 1%) | 1427 (< 1%) | 3063 (1%) | 2613 (2%) | 327 (4%) | 7440 (2%) | |
| Mixed | 20 (< 1%) | 864 (< 1%) | 941 (< 1%) | 531 (< 1%) | 52 (< 1%) | 2408 (< 1%) | |
| Asian | 84 (3%) | 3895 (3%) | 4643 (2%) | 1937 (1%) | 111 (1%) | 10,670 (2%) | |
| Other | 54 (2%) | 1732 (1%) | 2522 (1%) | 1535 (1%) | 141 (2%) | 5984 (1%) | |
| Townsend Deprivation Index | Mean (SD) | −0.7 (3.4) | −1.5 (3.0) | −1.4 (3.0) | − 0.91 (3.2) | − 0.02 (3.4) | −1.3 (3.1) |
| Median (Q1, Q3) | −1.6 (−3.4, 1.7) | −2.3 (− 3.7, 0.2) | −2.3 (− 3.7, 0.3) | −1.76 (− 3.4, 1.2) | −.6 (− 2.8, 2.6) | −2.2 (− 3.7, 0.5) | |
| Missing | 5 | 183 | 239 | 138 | 13 | 578 | |
| Smoking Status | Yes | 570 (23%) | 17,726 (11%) | 20,949 (10%) | 10,479 (10%) | 810 (9%) | 429,176 (10%) |
| No | 1911 (77%) | 139,001 (88%) | 183,417 (89%) | 96,904 (90%) | 7943 (90%) | 50,534 (89%) | |
| Missing/Prefer Not to Answer | 13 (< 1%) | 603 (< 1%) | 1041 (1%) | 699 (< 1%) | 61 (1%) | 2417 (1%) | |
| TOTAL | 2494 (0.1%) | 157,330 (32.6%) | 205,407 (42.6%) | 108,082 (22.4%) | 8814 (1.8%) | 482,127 (100%) | |
| Estimated UK National Averagea | < 1% | 27% | 39% | 30% | 4% | – | |